Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 5878
  • Home
  • Print this page
  • Email this page
Cover page of the Journal of Health Sciences
ORIGINAL ARTICLE
Year : 2023  |  Volume : 16  |  Issue : 1  |  Page : 54-59

Comparative evaluation of antifungal efficacy and potency of soft liners incorporated with powder extracts of Lawsonia inermis and Withania somnifera on the growth of Candida albicans – An in vitro study


1 Department of Prosthodontics, Kaher's KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India
2 Basic Science Research Center, Belagavi, Karnataka, India

Correspondence Address:
Dr. Rahul Suresh Jaiswal
Nehru Nagar, Belagavi, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kleuhsj.kleuhsj_36_22

Rights and Permissions

CONTEXT: Denture relining materials are soft and resilient materials used in the treatment of patients with denture soreness. Studies have concluded that rugged surface of the liners allows the sticking of the Candida albicans and later gives rise to a condition called denture-induced stomatitis. AIMS: The aim of this study is to evaluate and compare the antifungal efficacy and potency of denture soft liners incorporated with powder extract of Lawsonia inermis and Withania somnifera on the growth of C. albicans. MATERIALS AND METHODS: A total of 105 samples were taken in this in vitro study and was divided into three groups: To check for the antifungal activity with 35 samples each. L. inermis and W. somnifera powder extract were incorporated in soft liner at 1%, 3%, 5%, and 7% concentration and the antifungal efficacy against C. albicans was tested by calculating the diameter of inhibition zone for 1, 7, and 14 days. Statistical analysis used: Subgroup analysis was carried out using one-way analysis of variance (ANOVA) test. Pair-wise comparisons were carried out through Tukey's multiple post hoc procedures. RESULTS: When comparison of four subgroups (1%, 3%, 5%, and 7%) was done with the mean zone of antifungal efficacy at 1st day, 7th day, and 14th day time points in both the groups by one-way ANOVA, statistically significant results were obtained with P of 0.0001. CONCLUSIONS: L. inermis and W. somnifera natural herb extracts have shown to have antifungal activity against C. albicans and can be used as an alternative for the synthetic antifungal drugs.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed87    
    Printed6    
    Emailed0    
    PDF Downloaded15    
    Comments [Add]    

Recommend this journal