Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 287
  • Home
  • Print this page
  • Email this page
Cover page of the Journal of Health Sciences
Year : 2022  |  Volume : 15  |  Issue : 2  |  Page : 168-172

COVID-19-associated Guillain–Barre syndrome: A case series with review of literature

Department of Medicine, S P Medical College, Bikaner, Rajathan, India

Correspondence Address:
Dr Harish Kumar
B-3 Shastri Nagar, Bikaner - 334 001, Rajasthan
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/kleuhsj.kleuhsj_407_21

Rights and Permissions

Globally, millions of people are rapidly infected with COVID-19 and it has spread worldwide from January 2020 to till date. Coronavirus mostly affects the respiratory system; it can also result in several multisystem complications. This is a case series of four patients admitted in the department of medicine with post-COVID-19 Guillain–Barre syndrome (GBS). SARS-CoV-2 mainly affects the respiratory system but multiple organ damage is being reported recently, neurologic damage is one of them. SARS-CoV-2 causes neurologic damage including, by direct attack the nervous system through angiotensin-converting enzyme receptor, secondary to an immune reaction against SARS-CoV-2, retrograde transport, cytokine, and hypoxia-related injury. However, pathogenesis is not fully understood. It is hypothesized that the cause of GBS in covid patients is due to immune-mediated. It is hypothesized that inflammatory cytokines may play a role in an immune-mediated neuropathy. In this era of pandemic, we are concern about the involvement of respiratory and gastrointestinal systems only, involvement of other systems is underestimated. It is very important to be aware of association of GBS with COVID-19. Although neurological involvement in COVID-19 is rare, early diagnosis and treatment can reduce morbidity and mortality. We should always think about COVID-19 infection in a patients presented with GBS after respiratory or gastrointestinal involvement.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal