Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 406
  • Home
  • Print this page
  • Email this page
Cover page of the Journal of Health Sciences
ORIGINAL ARTICLE
Year : 2022  |  Volume : 15  |  Issue : 1  |  Page : 70-75

Role of structured exercise therapy on cognitive markers and stress parameters in young patients with Type 2 diabetes mellitus


1 Department of Physiology, JN Medical College, Belagavi, Karnataka, India
2 Department of Medicine, JN Medical College, Belagavi, Karnataka, India

Correspondence Address:
Dr. Harpreet Kour
Department of Physiology, JN Medical College, Belagavi, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kleuhsj.kleuhsj_287_21

Rights and Permissions

BACKGROUND AND AIMS: Diabetes mellitus (DM) patients face cognitive impairments owing to neuronal dysfunction following constant oxidative stress. The influence of exercise therapy in the management of DM is widely recognized among the elderly. However, its role among young adults in India is not explored. This study aimed to assess the effect of structured exercise on cognitive markers and stress parameters in young DM patients. MATERIALS AND METHODS: This interventional study with a pre- and post-model was conducted among 48 newly diagnosed type 2 DM patients who were asymptomatic for cognitive dysfunctions. Glucose profile was recorded by commercially available kits. Cognitive function markers and stress parameters, namely, Tau Protein was estimated in plasma samples using enzyme-linked immunoassay Kit, nitric oxide (NO) by colorimetric method, Catalase and malondialdehyde (MDA) assay by the spectrophotometric method. Patients were trained for the structured exercise therapy as per the protocol and evaluated at the end of 6 months. The change in the quantitative parameters before and after the intervention was assessed by paired t-test. P < 0.05 was considered statistically significant. RESULTS: The mean of Tau protein, catalase NO, and MDA showed significant statistical difference (P < 0.001) when compared from baseline to postintervention. However, the mean of fasting blood glucose (P = 0.8705), postprandial blood glucose (P = 0.8121), and glycated hemoglobin (P = 0.8121) reported insignificant values from baseline to postintervention. CONCLUSIONS: Integrated approach of structured exercise therapy has improved the cognitive functions and decreased oxidative stress.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed310    
    Printed8    
    Emailed0    
    PDF Downloaded46    
    Comments [Add]    

Recommend this journal